Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Enterprise Ireland Innovation Partnership Funded Research Project

The experimental work carried out during this project accelerated our efforts to bring these materials to the market and provide the potential to have a direct impact on the quality of life of patients suffering from degenerative bone and joint diseases

Pat Forristal
Chairman
SurgaColl

Project Title

Biomaterials for bone and cartilage repair

Engagement type

Enterprise Ireland Innovation Partnership Funded Research Project

Industry partner

SurgaColl™ Technologies, an RCSI Spin-out company, is commercialising a range of biocompatible, bioactive, and naturally-derived scaffolds to faster, higher quality bone and cartilage regeneration.

Challenge

Bone grafts are second only to blood transfusions on the list of transplanted materials worldwide. Autogenous bone, currently the clinical “gold-standard” is not always ideal due to availability of donor tissue and donor site morbidity. Cartilage damage resulting from osteoarthritis affects more than 10% of the US population over 25 years of age, making it the most common form of degenerative joint disease. Regeneration of hyaline cartilage is one of the most elusive challenges facing researchers in the orthopaedic industry today. This project focused on robust preclinical evaluation of two pipeline SurgaColl materials to address these significant clinical needs.

RCSI value-add

World class biomaterials research expertise (based in RCSI's Tissue Engineering Research Group in the Dept. of Anatomy) in restoring the structural and functional properties of damaged or degenerated tissue and mature collaborative relationships with leading Irish and International research centres.