Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Publications 2018

Boakye D, Wyse CA, Morales-Celis CA, Biello SM, Bailey MES, Dare S, Ward J, Gill JMR, Pell JP, Mackay DF. Tobacco exposure and sleep disturbance in 498 208 UK Biobank participants  J Public Health (Oxf). 2017 Aug 30:1-10. PMID: 29040744.

Byrne T, Nelson L, Beirne JP, Sharpe D, Quinn JE, McCluggage WG, Robson T, Furlong F.  BRCA1 and MAD2 Are Coexpressed and Are Prognostic Indicators in Tubo-ovarian High-Grade Serous Carcinoma. Int J Gynecol Cancer. 2018 Mar;28(3):472-478.  Int J Gynecol Cancer. 2018 Mar;28(3):472-478.  PMID:29465507.

Colas RA, Souza PR, Walker ME, Burton M, Marques RM, Zaslona Z, Curtis AM, Dalli J.  Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increases Systemic Inflammation and Cardiovascular Disease. Circ Res. 2018 Mar 16;122(6):855-863. PMID: 29437834.

Curtin C, Nolan JC, Conlon R, Tan YJ, Gallagher C, Deneweth L, Cavanagh BL, Asraf AZ, Bray I, Harvey H, Miller-Delaney S, O'Brien FJ, Stallings RL, Piskareva O.  A physiologically relevant 3D collagen-based scaffold - neuroblastoma cell system exhibits chemosensitivity similar to orthotopic xenograft models. Acta Biomater. 2018 Apr 1;70:84-97.  PMID: 29447961.

Das S, Moran B, Perry A. Assessing DNA methylation in cancer stem cells. Methods Mol Biol.  2018;1692:157-178. PMID: 28986896.

Fallon PG, Lavin M, O'Donnell JS. SIPPET - insights into factor VIII immunogenicity. J Thromb Haemost. 2018 Jan;16(1):36-38 PMID: 29080389.

Fogarty H,  Doyle MM, Campbell RC,  Keenan C, White B, Ryan K, O’ Donnell J, Slevin J, O’Keeffe D, O’Connell NM, Lavin M.  Management of combined factor V and factor VIII deficiency in pregnancy. J Obstet Gynaecol. 2018 Apr 18:1-2. PMID: 29667457. 

Garciarena CD, Malik A, Swietach P, Moreno AP, Vaughan-Jones RD.  Distinct moieties underlie biphasic H+ gating of connexin43 channels, producing a pH optimum for intercellular communication. FASEB J. 2018 Apr;32(4):1969-1981   PMID: 29183963. 

Gilbert E, O'Reilly S, Merrigan M, McGettigan D, Molloy AM, Brody LC, Bodmer W, Hutnik K, Ennis S, Lawson DJ, Wilson JF, Cavalleri GLThe Irish DNA Atlas: Revealing fine-scale population structure and history within Ireland. Sci Rep. 2017 Dec 8;7(1):17199. PMID: 29222464.

Kavanagh N, Ryan EJ, Widaa A, Sexton G, Fennell J, O’Rourke S, Cahill KC, Kearney CJ, O’Brien FJ, Kerrigan SW. Staphylococcus Osteomyelitis – Disease progression, treatment challenges and future directions.  Clin Microbiol Rev. 2018 Feb 14;31(2).  PMID: 29444953.

Kennedy C, Wong L , Sexton DJ, Cowman J, Oglesby I, Kenny M , Conlon P, and Kenny D.  Successful kidney transplantation normalizes platelet function.  Clinical Kidney Journal, 2018, 1–7. doi: 10.1093/ckj/sfx148.

Kenny C, McDonagh N, O’Meara E, Klinger R, O’Connor DP, Roche F, Hokamp K, O’Sullivan MJ. Dysregulated cell signalling as an oncogenic basis for the development of clear cell sarcoma of the kidney (CCSK)  J Pathol. 2018 Mar;244(3):334-345.  PMID: 29243812.

Lavin M, Ryan K, White B, Byrne M, O'Connell NM, O'Donnell JS. A role for intravenous immunoglobulin in the treatment of Acquired Von Willebrand Syndrome associated with IgM gammopathy.   Haemophilia. 2018 Jan;24(1):e22-e25. PMID:  29168278. 

Lickert S, Sorrentino S, Studt J. D, Medalia O, Vogel V, Schoen I.  Morphometric analysis of spread platelets identifies integrin αIIbβ3-specific contractile phenotype.  Sci Rep. 2018 Apr 3;8(1):5428. PMID: 29615672. 

Lyall LM, *Wyse CA, Celis-Morales CA, Lyall DM, Cullen B, Mackay D, Ward J, Graham N, Strawbridge RJ, Gill JMR, Ferguson A, Bailey MES, Pell JP, Curtis AM, Smith DJ.  Seasonality of depressive symptoms in women but not in men: A cross-sectional study in the UK Biobank cohort.  J Affect Disord. 2018 Jan 4;229:296-305.PMID: 29329063. [equal contributions].

Lyons VG, Payne NL, McCoy CE. Optimization Techniques for miRNA expression in low frequency immune cell populations. Methods Mol Biol.  2018;1725:237-256.  PMID: 29322422.

McCarthy NS, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S,  et al incl. Stanton AV. Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Atherosclerosis. 2017 Dec 8;269:42-49. PMID:29258006

McCormack M, Gui H,  Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, et al, incl. Delanty N, Cavalleri G.  Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Neurology. 2018 Jan 23;90(4):e332-e341. PMID: 29288229. 

McDonnell CJ, Soule EE, Walsh PT, O'Donnell JS, Preston RJS. The Immunoregulatory Activities of Activated Protein C in Inflammatory Disease.  Semin Thromb Hemost. 2018 Mar;44(2):167-175  PMID: 29232721. 

Nejad C, Pillman KA, Siddle KJ, Pepin G, Änkö ML, McCoy CE,  et al.  miR-222 isoforms are differentially regulated by type-I interferon. RNA. 2018 Mar;24(3):332-341.    PMID:29263133. 

O'Grady S, Morgan MP. Microcalcifications in breast cancer: From pathophysiology to diagnosis and prognosis. Biochim Biophys Acta. 2018 Apr 21;1869(2):310-320.  PMID: 29684522.  

O'Halloran JA, Dunne E, Tinago W, Denieffe S, Kenny D, Mallon PWG.  Switching from abacavir to tenofovir disoproxil fumarate is associated with rises in soluble glycoprotein VI, suggesting changes in platelet-collagen interactions.  
AIDS. 2018 Apr 24;32(7):861-866.  PMID:  29438200.

Olsson AAlfredsson JRamström SSvedjeholm RKenny D, Håkansson EBerglund JSBerg S.  Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique - a randomized pilot study.  Perfusion. 2018 Apr;33(3):185-193.   PMID: 28950757.

O'Sullivan JM, Preston RJSRobson TO'Donnell JS.  Emerging roles for von Willebrand Factor in cancer cell biology. Semin Thromb Hemost. 2018 Mar;44(2):159-166.    PMID: 29165741.  

Ren Z, Yan P, Zhu L, Yang H, Zhao Y, Kirby BP, Waddington JL, Zhen X. Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation. Psychopharmacology (Berl). 2018 Jan;235(1):233-244. PMID: 29058041.

Ryan AJ, Kearney CJ, Shen N, Khan U, Kelly AG, Probst C, Brauchle E, Biccai S, Carciarena CD, Kerrigan SW, Kelly DJ, Schenke-Layland K, Coleman JN, O'Brien FJ. Electroconductive biohybrid collagen and pristine graphene composite biomaterials with enhanced biological activity. Advanced Materials 2018 Apr;30(15):e1706442     PMID: 29504165.

Sheilds S, Conroy E, O' Grady T, McGoldrick A, Connor K, Ward M, Useckaite Z, Dempsey E, Reilly R, Fan Y, Chubb A, Matallanas D, Kay E, O' Connor D, McCann A, Gallagher WM,  Coppinger JA .  BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in Triple Negative Breast Cancer.  Oncotarget. 2018; 9:15673-15690. 

Sutton CE, Finlay CM, Raverdeau M, Early JO, DeCourcey J, Zaslona Z, O'Neill LAJ, Mills KHG, Curtis AM. Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.  Nat Commun. 2017 Dec 12;8(1):1923. PMID: 29234010. 

Synnott N, Bauer MR, Madden S, Murray A, Klinger R, O'Donovan N, O'Connor DP, Gallagher WM, Crown J, Fersht AR, Duffy MJ. Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007.   Cancer Lett. 2018 Feb 1;414:99-106  PMID: 29069577. 

Villanueva V, Holtkamp M, Delanty N, Rodriguez-Uranga J, McMurray R, Santagueda P.   Euro-Esli: a European audit of real-world use of eslicarbazepine acetate as a treatment for partial-onset seizures.   J Neurol. 2017 Nov;264(11):2232-2248.   PMID: 28921040.

Ward J, Dunne E, Bishop D, Boyd A, Kenny D, Meenan B. Entrapment of Autologous von Willebrand Factor on Polystyrene/Poly(methyl methacrylate) Demixed Surfaces.    Polymers 20179(12), 700; doi:10.3390/polym9120700

Ward SEO'Sullivan JM, Drakeford C, Aguila S, Jondle CN, Sharma J, Fallon PG, Brophy TM, Preston RJS, Smyth P, Sheils O, Chion AO'Donnell JS.    A novel role for the macrophage galactose-type lectin (MGL) receptor in mediating von Willebrand factor clearance. Blood. 2018 Feb 22;131(8):911-916.   PMID: 29282218.

Whelan CD, Altmann A, Botía JA, Jahanshad N, Hibar DP, Absil J, Alhusaini S, et al [incl. Cavalleri G]. Structural brain abnormalities in the common epilepsies  assessed in a worldwide ENIGMA study.  Brain. 2018 Feb 1;141(2):391-408  . PMID: 29365066.