Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Professor Brian Cleary

Brian Cleary

Prof. Brian Cleary BSc (Pharm), MSc
Honorary Clinical Associate Professor
Email: briancleary@rcsi.com 

Biography 
Prof. Brian Cleary graduated from the School of Pharmacy, Trinity College Dublin in 2001. Brian has worked in the Maternity Services since 2002, working initially in the Coombe Women and Infants University Hospital. He received his MSc in Clinical Pharmacy from Robert Gordon University, Aberdeen in 2006. In 2007 he took up a shared clinical-academic post between CWIUH and the School of Pharmacy, Royal College of Surgeons in Ireland. Brian completed his PhD in 2011 in the Department of Obstetrics and Gynaecology, TCD and was the first graduate of the Health Research Board's, PhD Scholars Programme in Health Services Research, now the SPHERE Programme. He took up the post of Chief Pharmacist in the Rotunda Hospital in 2013. In June 2014, Brian was promoted to Honorary Clinical Associate Professor within the School of Pharmacy. Brian has been the national clinical lead of the Medications Workstream of the Maternal and Newborn Clinical Management System since 2015. This project entails the introduction of electronic health records and electronic prescribing for all maternal and newborn care in Ireland.

Professional Committees
Drug and Therapeutics Committee, Rotunda Hospital 
Neonatal and Paediatric Pharmacists Group

Research Interests
Pharmacoepidemiological studies of the safety of medications during pregnancy
Systematic reviews/meta-analyses of the safety of medications during pregnancy
Management of opioid dependence in pregnancy
Preconception counselling and counselling of women with medication exposures in early pregnancy
Therapeutic drug monitoring in pregnancy
Medication Safety
Health Informatics

Publications
1. O'Shaughnessy F, Donnelly JC, Cooley SM, Deering M, Raman A, Gannon G, Hickey J, Holland A, Hayes N, Bennett K, Ní Áinle F, Cleary BJ. Thrombocalc: implementation and uptake of personalized postpartum venous thromboembolism risk assessment in a high-throughput obstetric environment. Acta Obstet Gynecol Scand. 2017 Nov;96(11):1382-1390. doi: 10.1111/aogs.13206. Epub 2017 Sep 21.

2. Gleeson J, Eogan M,
Cleary B. Detoxification from opiates during pregnancy: additional risks. Am J Obstet Gynecol. 2017 Jan;216(1):80. doi: 10.1016/j.ajog.2016.08.004. Epub 2016 Aug 10. 

3. Wuytack F, Smith V,
Cleary BJ. Oral non-steroidal anti-inflammatory drugs (single dose) for perineal pain in the early postpartum period. Cochrane Database Syst Rev. 2016 Jul 14;7:CD011352. doi: 10.1002/14651858.CD011352.pub2.

4.
Cleary BJ, Rice Ú, Eogan M, Metwally N, McAuliffe F. 2009 A/H1N1 influenza vaccination in pregnancy: uptake and pregnancy outcomes - a historical cohort study. Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:163-8. doi: 10.1016/j.ejogrb.2014.04.015. Epub 2014 Apr 18.

5. Vaughan DA,
Cleary BJ, Murphy DJ. Delivery outcomes for nulliparous women at the extremes of maternal age - a cohort study.BJOG. 2014 Feb;121(3):261-8. doi: 10.1111/1471-0528.12311. Epub 2013 Jun 12.

6. Murphy DJ, Mullally A,
Cleary BJ, Fahey T, Barry J. Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes--a prospective cohort study. BMC Pregnancy Childbirth. 2013 Jan 16;13:8. doi: 10.1186/1471-2393-13-8.

7.
Cleary BJ, Eogan M, O'Connell MP, Fahey T, Gallagher PJ, Clarke T, White MJ, McDermott C, O'Sullivan A, Carmody D, Gleeson J, Murphy DJ. Methadone and perinatal outcomes: a prospective cohort study. Addiction. 2012 Aug;107(8):1482-92. doi: 10.1111/j.1360-0443.2012.03844.x. Epub 2012.

8. Mullally A,
Cleary BJ, Barry J, Fahey TP, Murphy DJ. Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland. BMC Pregnancy Childbirth. 2011 Apr 11;11:27. doi: 10.1186/1471-2393-11-27.

9.
Cleary, B. J., Reynolds K, Eogan, M., O'Connell, M. P., Fahey, T., Gallagher, P.J., Clarke, T., White, M.J., McDermott, C, O'Sullivan, A., Carmody, D., Gleeson, J. & Murphy, D.J. (2012). Methadone dosing and prescribed medication use in a prospective cohort of opioid-dependent pregant women. Addiction In Press [epub ahead of print]

10.
Cleary BJ, Donnelly J, Strawbridge JD, Gallagher PJ, White MJ, Fahey T, Murphy DJ. Methadone and Perinatal Outcomes: a Retrospective Cohort Study. American Journal of Obstetrics & Gynecology 2011;204(2):139.e1-139.e9.

11.
Cleary BJ, Donnelly J, Strawbridge JD, Gallagher PJ, Clark M, Fahey T, Murphy DJ. Methadone Dose and Neonatal Abstinence Syndrome- Systematic Review and Meta-analysis. Addiction 2010;105(12):2071-2084.

12. McGuire M, Cleary BJ, Sahm L, Murphy DJ. Prevalence and predictors of periconceptional folic acid uptake--prospective cohort study in an Irish urban obstetric population. Human Reproduction 2010;25(2):535-543.

13. Cleary BJ, Butt H, Strawbridge JD, Gallagher PJ, Fahey T, Murphy DJ. Medication use in early pregnancy-prevalence and determinants of use in a prospective cohort of women. Pharmacoepidemiology and Drug Safety 2010;19(4):408-417.

14. Cleary BJ, Källén B. Early pregnancy azathioprine use and pregnancy outcomes. Birth Defects Research. Part A, Clinical and Molecular Teratology 2009;85:647-54.

15. Bolton S, Cleary B, Walsh J, Dempsey E, Turner MJ. Continuation of metformin in the first trimester of women with polycystic ovarian syndrome is not associated with increased perinatal morbidity. European Journal of Pediatrics 2009;168(2):203-206.