Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Dr Eoin Cotter

Eoin Cotter

Dr Eoin Cotter BSc, PhD
Technical & Laboratories Manager
Tel: +353 1 402 8528
Email: eoincotter@rcsi.com

Biography
Eoin Completed a BSc in Biotechnology in DCU in 2001, before undertaking a PhD in vascular biology at the same university. In 2005 joined UCD/MMUH as a postdoctoral researcher, examining the non-immunological effects of HIV infection and treatment, and most notably the role of Mesenchymal Stem Cells in these phenomena. In 2010 he became the senior scientist/scientific services manager of the UCD Clinical Research Centre, a role that entailed leadership of the development of laboratory, biobanking and analytical facilities at the CRC, and coordinated their deployment to support the numerous clinical trials and studies conducted within the CRC and other associated sites. In addition he also contributed to the design and delivery of the centre's extensive teaching program.

Professional Committees
National Consultative Committee IS0 TC276

Publications
1. Novel roles of neuropeptide processing enzymes: EC3.4.24.15 in the neurome. Kim SI, Grum-Tokars V, Swanson TA, Cotter EJ, Cahill PA, Roberts JL, Cummins PM, Glucksman MJ. J Neurosci Res. 2003 Nov 1;74(3):456-67.

2. Regulation of endopeptidases EC3.4.24.15 and EC3.4.24.16 in vascular endothelial cells by cyclic strain: role of Gi protein signaling. Cotter EJ, von Offenberg Sweeney N, Coen PM, Birney YA, Glucksman MJ, Cahill PA, Cummins PM. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):457-63. Epub 2004 Jan 15.

3. Hemodynamic regulation of metallopeptidases within the vasculature. Cummins PM, Cotter EJ, Cahill PA. Protein Pept Lett. 2004 Oct;11(5):433-42. Review

4. Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation. Von Offenberg Sweeney N, Cummins PM, Cotter EJ, Fitzpatrick PA, Birney YA, Redmond EM, Cahill PA. Biochem Biophys Res Commun. 2005 Apr 8;329(2):573-82.

5. HIV protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts. Malizia AP, Cotter E, Chew N, Powderly WG, Doran PP. AIDS Res Hum Retroviruses. 2007 Feb;23(2):243-50.

6. HIV proteins regulate bone marker secretion and transcription factor activity in cultured human osteoblasts with consequent potential implications for osteoblast function and development. Cotter EJ, Malizia AP, Chew N, Powderly WG, Doran PP. AIDS Res Hum Retroviruses. 2007 Dec;23(12):1521-30.

7. Mechanism of HIV protein induced modulation of mesenchymal stem cell osteogenic differentiation. Cotter EJ, Ip HS, Powderly WG, Doran PP. BMC Musculoskelet Disord. 2008 Mar 13;9:33.

8. Is PPARgamma a Prospective Player in HIV-1-Associated Bone Disease? Cotter EJ, Mallon PW, Doran PP. PPAR Res. 2009;2009:421376. Epub 2009 Mar 23.

9. Progenitor Cell Types in HIV-1 Infection; Bioactivity and Emerging Targets for Treatment. Cotter EJ, Doran PP, Powderly WG. Curr HIV Res. 2009 Sep 1.

10. HIV Type 1 Alters Mesenchymal Stem Cell Differentiation Potential and Cell Phenotype ex Vivo.. Cotter EJ, Chew N, Ip HSM, Powderly WG, Doran PP. AIDS Res Hum Retroviruses. 2010 Oct 7

11. Role Of Mesenchymal Stem Cells (MSC) In HIV-1 Associated Bone And Lipid Toxicities. Cotter EJ., Maughan RT., Doran PP. Stem Cells and Cancer Stem Cells. Vol. 8. Springer 2012 ed. Hayat EM.

12. HIV-associated osteoporosis in Ireland: prevalence and risk factors. 2012. Nicholas S Chew, Gerard S Sheehan, John Lambert, Samuel J McConkey, Eoin J Cotter, Peter P Doran & William G Powderly.. Vol. 7, No. 8, Pages 791-799 , DOI 10.2217/fvl.12.68

13. Expression of Neuroepithelial Transforming Gene 1 is Enhanced in Oesophageal Cancer and Mediates an Invasive Tumour Cell Phenotype. Lahiff C., Cotter E., Stroiescu A., Casey R., Doran P., Pidgeon G., Reynolds J., MacMathuna P., Murray D. Mol. J Exp Clin Cancer Res. 2013 Aug 14;32(1):55. doi: 10.1186/1756-9966-32-55.

14. Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism? Coss. KP, Treacy EP, Cotter EJ, Knerr I, Murray DW, Shin YS, Doran PP. Mol. Genetics and Metabolism. Aug 2014