Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Dr Joanne Ramsey

Joanne Ramsey

Dr Joanne M. Ramsey BSc (Hons), DPP, PhD
Postdoctoral Researcher
Email: joanneramsey@rcsi.com

Biography
Joanne graduated from University of Ulster in 2007 with a degree in Biomedical Science and Diploma in Professional Practice (DPP). She carried out her PhD in the Centre for Cancer Research and Cell Biology at Queen's University Belfast where she studied small molecule therapies in malignant diseases. Upon completion of her PhD in 2011 she took up a postdoctoral research position in Prof Sally-Ann Cryan's lab in RCSI studying non-viral gene delivery for respiratory and malignant diseases. Joanne was appointed honorary lecturer in 2014 and lecturer in pharmaceutics in the School of Pharmacy in 2015, and will commence supervision of a Government of Ireland (Irish Research Council) PhD student in October 2015.

Research Interests
Nanoparticle and microparticle drug delivery systems
Respiratory drug delivery
Targeted nanotherapies in lung and brain cancer
Bioresponsive drug delivery systems
In vivo evaluation of convergent drug delivery platforms

Publications
1. Byrne M, Murphy R, Kapetanakis A, Ramsey JM, Cryan SA*, Heise A. Star-Shaped Polypeptides: Synthesis and Opportunities for Delivery of Therapeutics. In Press. Macromolecular Rapid Communications.

2. Kelly C, Lawlor C, Burke C, Barlow JW, Ramsey JM, Jefferies C, Cryan SA. High-throughput methods for screening liposome-macrophage cell interaction. J Liposome Res. 2014 Dec 30:1-11.

3. Kelly C, Yadav AB, Lawlor C, Nolan K, O'Dwyer J, Greene CM, McElvaney NG, Sivadas N, Ramsey JM, Cryan SA. Therapeutic Aerosol Bioengineering of siRNA for the Treatment of Inflammatory Lung Disease by TNFa Gene Silencing in Macrophages. Molecular Pharmaceutics. 2014 Nov 3; 11(11):4270-9.

4. Mulgrew NM, Kettyle LM, Ramsey JM, Cull S, Smyth LJ, Mervyn DM, Bijl JJ, Thompson A. c-Met inhibition in a HOXA9/Meis1 model of CN-AML. Developmental Dynamics. 2014 Jan; 243(1):172-81.

5. Ramsey JM, Hibbitts A, Barlow J, Kelly C, Sivadas N, Cryan SA. Smart non-viral delivery systems for targeted delivery of RNA to the lungs. Therapeutic delivery. 2013 Jan; 4 (1): 59-76.

6. Ramsey JM, Kettyle LMJ, Sharpe DJ, Mulgrew NM, Dickson GJ, Bijl JJ, Austin P, Mayotte N, Cellot S, Lappin TRJ, Zhang SD, Mills KI, Krosl J, Sauvageau G, Thompson A. Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of CN-AML. Stem Cells. 2013 Jul; 31(7):1434-45.

7. Wheadon H, Ramsey JM, Dobbin E, Dickson GJ, Corrigan PM, Freeburn RW, Thompson A. Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis. Stem cells and Development. 2011 Aug; 20(8): 1465-76.