Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Available Research Projects

Funded PhD: Dr Helen French and Louise Keating - Injury Surveillance of Schoolboys’ Level Rugby

This is an exciting and unique opportunity for an ambitious student researcher to join Dr Helen French and Louise Keating, School of Physiotherapy, RCSI working on Injury Surveillance of Schoolboys’ Level Rugby. More Information.


PhD: Dr Marian Brennan - Drug Development

This project will aim to develop of a novel biotherapeutic for the treatment of cystinosis. More Information.


PhD: Prof Mary Cannon - Psychiatric epidemiology

The aim of this project is to investigate the meanings and mechanisms of psychotic experiences in young people More Information.


FUNDED PhD: Dr Cian O'Leary - Bioengineering, Regenerative Medicine

The project seeks to find a highly-motivated student to carry out a study focused on: Development of an Implantable Bioengineered Tracheal Scaffold for Respiratory Tissue Regeneration More Information.


FUNDED PhD: Dr. Annie Curtis and Dr Cathal Kearney - Timed to Perfection: Development of a novel circadian drug delivery platform

PhD Studentship - Development of a novel circadian drug delivery platform and its application in osteoarthritis. Funded by the SFI AMBER centre. More Information.


Dr. Declan Patton - 2 PhD Scholarships in Wound care

This funded project will focus on the use of technology to better assess Diabetic Foot Ulceration. More Information.


PhD: Dr Claire McCoy - Investigating nanomodulation of microRNAs in macrophages

This PhD project will specifically focus on investigating how to deliver nanoparticles encapsulating microRNA inhibitors into macrophages More Information.


Funded PhD: Dr Annie Curtis - the role of the molecular clock in controlling metabolism within innate immune cells - circadian immunometabolism

The purpose of the PhD is to uncover metabolic signals that are regulated by the molecular clock and alter the inflammatory response. This project will impact our understanding of how we treat inflammatory diseases but also the time-of-day we treat inflammatory diseases. The project will utilise state-of-the-art techniques such as metabolic profiling, proteomics, RNA sequencing, flow cytometry, cellular imaging and electron microscopy. This project will also benefit from in vivo models of molecular clock ablation and of clock disruption. More Information.


Four fully-funded PhDs: HRB CDA ‘Right Care’ PhD programme

The ‘Right Care’ PhD programme is a Collaborative Doctoral Award funded by the Health Research Board. This programme is offering four doctoral awards that will enable structured methodological training to a cohort of multi-disciplinary PhD candidates from both clinical and non-clinical backgrounds. More Information.


Funded PhD: Prof. Fergal O'Brien - Dept of Anatomy

The aim of this research programme is to develop novel functionalised collagen-based scaffolds for the delivery of nucleic acid-based therapeutics using novel nanoparticle formulations in combination with 3D printed biomaterials. These scaffolds will be used as platforms for the repair of large volume osteochondral defects. More Information.


Funded PhD - FutureNeuro - Prof. David Henshall

This PhD project is an excellent opportunity to be involved in FutureNeuro - SFI Research Centre for neurological diseases. More Information.


Five FUNDED PhD studentships

StAR International PhD Programme - Five fully-funded PhDs with attractive relocation and travel allowance. More Information.


Part-funded MD - Professor Sam McConkey - radiology and immunology study

An MD candidate is sought for a joint radiological and immunology study, to optimise the efficacy and safety of the administration of vaccines in adults More Information.


FUNDED PhD: Dr Darran O’Connor and Prof. Jochen Prehn - Cancer Systems Biology/Bioinformatics

The aim of this project is to develop a novel decision support tool for Her2+ breast cancer. More Information.


PhD: Dr Ingmar Schoen - Spatiotemporal coordination of platelet behaviour during thrombus formation

The aim of this PhD project is to better understand how platelet mechanics contribute to different stages of thrombus formation. More Information.


PhD: Prof. Fergal O'Brien - Dressing4scars

Dressing4scars aims to develop a '4D printing' approach to develop smart responsive skin dressings capable of changing properties while wound healing/skin repair is taking place. More Information.


PhD: Prof. Fergal O'Brien - Development of advanced biomaterials for bone and cartilage regeneration

The aim of this project is to enhance the bone and cartilage-forming potential of materials developed by TERG/SurgaColl by using DNA or RNA, to control mesenchymal stem cell hypertrophy. More Information.


PhD: Dr Zeibun Ramtoola - Development of targeted nanomedicines in the treatment of IBD

This project aims to investigate the potential therapeutic effectiveness of oral nanomedicines currently under development in RCSI. More Information.


PhD: Dr Brona Murphy - Improving Treatment Options for Glioblastoma Patients

The aim of this PhD is to investigate the therapeutic efficacy of CDK inhibitors for GBM patients. More Information.


PhD: Dr Darren Griffith - Combating Antibiotic Resistance with Novel Bismuth-Biomolecular Conjugates

During this project, candidates will develop bismuth conjugates, which possess (i) the antibacterial properties of bismuth and (ii) antimicrobial and targeting properties associated with specific biomolecules of interest and will overcome bacterial resistance. More Information.


PhD: Dr Oran Kennedy - Bone-Cartilage Crosstalk in Post Traumatic Osteoarthritis after Acute Joint Injury

The aim of this PhD project is to develop novel cell-culture and animal models to understand the role of subchondral bone in PTOA initiation and progression. More Information.


PhD: Dr Marco Monopoli - Biomarker Assay for Precision Medicine

Candidates are currently being sought for an IRC grant application submission for a PhD by research in Biomarker Assay Development. More Information.


MSc: Dr Declan Patton - Management of venous leg ulcers

Two candidates are currently being sought for submission of an IRC grant application for a Masters by research in the management of venous leg ulcers. More Information.


FUNDED PhD: Dr Oran Kennedy - Arthritis, Joint Disease, Mechanobiology

The project seeks to find a highly motivated student to investigate the role of subchondral bone in post-traumatic osteoarthritis (PTOA), which typically affects a younger population (often highly active, such as athletes) compared with age-related osteoarthritis. The successful candidate will be based in the Tissue Engineering Research Group at RCSI applying novel approaches to detect PTOA progression and investigating drug delivery systems that will mitigate joint degeneration. More Information.


PhD: Maria Morgan - Molecular & Cellular Therapeutics

This project will address the role of hydroxyapatite in M1/M2 macrophage differentiation and the potential biological consequences of hydroxyapatite-derived macrophages in exacerbating tumor progression. More Information.


PhD: Tracy Robson - Molecular & Cellular Therapeutics

This project brings together the expertise staff within Molecular & Cellular Therapeutics and collaborators within the pharmaceutical industry. More Information.


PhD: Dr Marco Monopoli - Pharmaceutical and Medical Chemistry

Nanoparticles are believed to radically change the way we treat diseases. Because of their small size, they can directly interact with biomolecules in a completely different way and their behavior in biology is still not fully understood. More Information.


Exosomes trigger tumour neovascularisation and and subsequent escape from chemotherapy

Olga Piskareva, Molecular & Cellular Therapeutics. Keywords: cancer, neuroscience, drug resistance, angiogenesis, exosomes. More Information.


Network meta analysis of psychological factors influencing health behaviours

Frank Doyle, Psychology. Keywords: cancer, cardiovascular disorders, respiratory diseases, population health, gynaecology, obstetrics & perinatal health, network meta-analysis, health behaviours, psychological factors. More Information.


Depression and health behaviours in chronic conditions

Frank Doyle, Psychology. Keywords: cardiovascular disorders, respiratory diseases, population health, depression, behaviour change, adherence. More Information.


Adherence to inhaled therapies

Frank Doyle, Psychology. Keywords: respiratory diseases, inhaled therapy, adherence, behaviour change. More Information.


Psychometrics of patient reported outcomes

Frank Doyle, Psychology. Keywords: population health, patient reported outcomes, item response theory, psychometrics. More Information.


Provision of smoking cessation care in hospital settings

Frank Doyle, Psychology. Keywords: cancer, cardiovascular disorders, respiratory diseases, population health, medical education, smoking, behaviour change, medical education. More Information.


Attitudes to organ donation

Frank Doyle, Psychology. Keywords: population health, organ donation, attitudes, intervention. More Information.


Breast cancer microcalcification-induced local inflammation; potential consequences for tumour progression

Maria Morgan, Molecular & Cellular Therapeutics. Keywords: cancer, breast cancer, cell biology, immunology. More Information.


Automated flow micro-reactors and parallel microwave-assisted synthesis

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry. More Information.


Mixed Li/K amides and enantioselective carbolithiations as effective synthetic tools

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry. More Information.


New class of light activated anti-cancer and anti-microbial agents

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: cancer, pharmacy, pharmaceutical sciences & chemistry, photodynamic therapy (pdt), anti-cancer, anti-microbial. More Information.


New class of near-infrared (NIR) fluorochrome for real-time fluorescence guided surgery

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry, nir fluorochrome, fluorochrome imaging, cancer. More Information.


Injectable chemotherapeutic gels for the treatment of glioblastoma multiforme

Eduardo Ruiz-Hernandez, Department of Anatomy and School of Pharmacy. Keywords: cancer, bioengineering, pharmacy, pharmaceutical sciences & chemistry, drug delivery systems, injectable gels, glioblastoma. More Information.


The Role of Platelets in Human Pregnancy: An exploration of the nature of the cytokine secretion profile during normal human pregnancy

Niamh Moran, Molecular & Cellular Therapeutics. Keywords: gynaecology, obstetrics & perinatal health, pregnancy, platelet, non-thrombotic. More Information.


Movement analysis of sports-related hip and groin pain

Helen French, School of Physiotherapy. Keywords: physiotherapy, 3D motion analysis, hip pain, movement screening. More Information.


The Role of Platelets in Cancer: An exploration of the nature of the cytokine secretion profile in during cancer progression

Niamh Moran, Molecular & Cellular Therapeutics. Keywords: cancer, cardiovascular disorders, platelet, metastasis More Information.


Novel peptidomimetics of Nature's antibiotics

Marc Devocelle, Pharmaceutical and Medicinal Chemistry. Keywords: Infection & Immunity, Peptidomimetics, Antimicrobial Peptides, Antibiotic resistance. More Information.


Nanomedicines against multi-drug resistant bacteria

Marc Devocelle, Pharmaceutical and Medicinal Chemistry. Keywords: Infection & Immunity, Antibiotic resistance, Antimicrobial Peptides, Prodrugs and nanomedicines. More Information.