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Visiting Research Fellows
Dr John Gleeson
Dr. Gleeson is a graduate in mechanical engineering from Trinity College Dublin (2001) and received his PhD in 2006, investigating the effect of early stage primary osteoarthritis on bone composition and mechanical properties. He is a Principal Investigator and Project and Business Development Manager in the Tissue Engineering Research Group, headed by Prof. Fergal O’Brien, in the Royal College of Surgeons in Ireland. His current role involves the development and commercialisation of novel tissue engineering medical devices for the repair and regeneration of bone and osteochondral tissue. Dr. Gleeson’s research interests include bone and cartilage mechanobiology, biomaterials, osteoarthritis and orthopaedic tissue engineering.
Current Project (Funding Source): Collagen-hydroxyapatite composite scaffolds as bone graft substitutes (Enterprise Ireland)
Dr Caroline Curtin
Caroline is a graduate in Biomedical Science from the National University of Ireland, Galway (NUI, Galway). She subsequently carried out research for her PhD in the area of adult stem cell therapeutics for osteoarthritic disease under the supervision of Prof. Frank Barry in the Regenerative Medicine Institute (REMEDI) in NUI, Galway. From February 2008 to December 2009, she worked as a research assistant within the Cellular Arthroplasty for Regeneration in Arthritis (CARA) group in NUI, Galway. She joined the Anatomy Department in RCSI as a postdoctoral researcher in January 2010 and her area of research focuses on gene therapy and bone tissue engineering.
Current Project (Supervisor and Funding Source): Osteoinductive and angiogenic smart scaffolds for bone tissue regeneration (Fergal O'Brien and European Research Council)
Dr Tanya Levingstone
Tanya is a graduate in Medical Mechanical Engineering from Dublin City University. She carried out research for her PhD in the area of plasma sprayed hydroxyapatite coatings in the National Centre for Plasma Science and Technology (NCPST) in Dublin City University and was awarded her PhD in 2008. Tanya currently works as a postdoctoral researcher in the Bone and Tissue Engineering Research Group in the RCSI where her main research focus is in the area of cartilage tissue engineering.
Current Project (Supervisor and Funding Source): Polyphasic collagen-based composite scaffolds for osteochondral defect repair (Fergal O'Brien and Enterprise Ireland)
Dr Andrew Cameron
Andrew completed his Bachelor of Engineering at the University of Queensland, with a double major in Chemical and Biological Engineering. Here, he then went on to complete a PhD in the Tissue Engineering and Microfluidics group at the Australian Institute of Bioengineering and Nanotechnology. His thesis analysed the influence of viscoelastic biomaterial properties on mesenchymal stem cell behaviour and phenotype. While finishing his PhD, Andrew also completed a Graduate Certificate in Research Commercialisation. His primary area of research at the RCSI is the development of films from natural materials for use in corneal tissue regeneration. He also works on other projects elucidating the change in cell response to mechanical stimulation when affected by age and disease conditions.
Current Project (Supervisor and Funding Source): Fabrication of carriers for limbal stem cell transplantation (Fergal O'Brien and SFI TIDA, Enterprise Ireland, Irish Research Council), Mechanobiology project (Fergal O'Brien and HRB, Children's Fund For Health, Children's University Hospital Temple Street)
Dr Amro Widaa
Amro Widaa received his B.Sc. (Hons) in Molecular & Cellular Biology from the National University of Ireland (NUI), Maynooth. He then went on to the Regenerative Medicine Institute in NUI Galway, in which he obtained his M.Sc. in Regenerative Medicine. Amro was awarded a multi-disciplinary Ph.D. researching the pathology of host infections at RCSI under the co-supervision of Prof. Fergal O'Brien and Dr. Steven Kerrigan. His completed Ph.D. is entitled "Staphylococcal Induced bone loss & destruction in Osteomyelitis".
Current Project (Supervisors and Funding Source): Scaffold based systems for the delivery of antimicrobials for the treatment of microbial infections and enhancement of tissue regeneration (Prof. Fergal O'Brien, this research is co-funded by Enterprise Ireland and the European Regional Development Fund (ERDF) under the National Strategic Reference Framework (NSRF) 2007-2013).
Amos is a graduate in Biomedical Engineering from The University of Sheffield where he attained an MEng. His thesis was on the mechanical stimulation of bone cells using bioreactor systems. During his course, he took up an undergraduate research placement in the Kroto Research Institute, University of Sheffield investigating the potential of polymers in peripheral nerve repair applications. His current research interest at RCSI is on cartilage defect repair using poly-phasic collagen scaffolds under the supervision of Prof. Fergal O'Brien and Dr. John Gleeson.
Current Project (Supervisor and Funding Source): Polyphasic collagen-based composite scaffolds for osteochondral defect repair (Fergal O'Brien/John Gleeson and Enterprise Ireland)
Greg completed his B.S.E in Bioengineering at the University of Pennsylvania, and joined the Tissue Engineering Research Laboratory led by Prof Steven B. Nicoll. He then completed a Ph.D. in the Orthopaedic and Developmental Biomechanics Laboratory at Boston University under the supervision of Prof Elise F. Morgan. His thesis was titled ‘Mechanoregulation and Mechanotransduction in Skeletal Tissue Differentiation‘ and involved the identification and quantification of mechano-regulatory mechanisms (strains) directing skeletal tissue differentiation in vivo and mechanotransduction proteins involved in the cell molecular response to mechanical stimulation, as well as the development and validation of the use of nanoindentation to characterize the mechanical properties of bone fracture callus soft-tissues. Greg joined the research group in the RCSI in 2013, with his main research focus in the areas of mechanobiology and bone tissue engineering.
Current Project (Supervisor and Funding Source): The Development of Placental Growth Factor-Functionalised, Collagen-Based Scaffolds for Promoting Vascularisation and Bone Repair (Fergal O'Brien and the Irish Research Council)
Clinical Postgraduate Students
| Dr Robert Thomas Brady
Robert completed a dual undergraduate degree in Pharmacology and Molecular Genetics at the Conway Institute of Biomolecular & Biomedical Research, University College Dublin. He then obtained his Batchelors of Medicine at RCSI. He returned to the college to pursue a PhD under the guidance of Prof. Fergal O'Brien and Dr. David Hoey with research focussed on bone mechanobiology and osteoporosis.
Current Project (Supervisor and Funding Source): Factors influencing mechanical loading induced bone formation (Fergal O'Brien, David Hoey and European Research Council)