Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

FUNDED PhD: Dr Stephen Keely - Targeting Bile Acids for the Treatment of Chronic Intestinal diseases

This PhD project will focus on developing bile acids as novel therapeutics for common intestinal disorders, such as inflammatory bowel diseases, irritable bowel syndrome, and colorectal cancer.

Project description

Applications are invited for a PhD studentship funded by Science Foundation of Ireland to investigate molecular mechanisms that regulate intestinal physiology in health and disease. Specifically, this project will focus on developing bile acids as novel therapeutics for common intestinal disorders, such as inflammatory bowel diseases, irritable bowel syndrome, and colorectal cancer.

This multidisciplinary project is being carried out in collaboration with researchers in Ireland and abroad and techniques will include cell and molecular biology approaches, electrophysiology, microscopy, and proteomics. Candidates should have a strong interest in cellular and molecular physiology.

The research will be conducted at RCSI, Molecular Medicine Laboratories, Beaumont Hospital, Dublin. The studentship will commence in December 2017 for a four-year period with a stipend of €18,000 per annum.

  • Research area: Gastrointestinal physiology/epithelial biology
  • Department:Molecular Medicine
  • Tenure: Four years
  • Salary: €18,000 per year (plus fees)

Specification

The successful candidate should be able to demonstrate the following: 

Essential

  • An Honours Bachelor degree (grade 2.1 or above) in biomedical science 
  • Good communication skills
  • Strong organisational and administrative skills
  • Ability to work on one’s own initiative as well as in a multidisciplinary, team environment
  • Willingness to undertake training and career development
  • English language requirements for candidates who do not speak English as their first language: an IELTS score of 6.5 or above

Desirable

  • Prior experience in cell culture and molecular techniques would be advantageous

 

Application process

Please apply here with the following:

  • An up-to-date CV
  • A completed application form (available from the application portal
  • A 500-word cover letter outlining your interest in and suitability for the position
  • Scanned transcripts (preferred), or detailed degree grade breakdown
  • Contact details of two referees

 

  • Application deadline: Monday, 18 September 2017.
  • Start date: 1 December 2017

Mentors Dr Stephen Keely