Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

FUNDED PhD: Dr Tobias Engel - Epilepsy

The project seeks to find a highly-motivated student to carry out a study focused on the impact of ATP-gated purinergic signalling on seizures and the development of epilepsy.

Project description

A four-year PhD studentship is available in the laboratory of Dr Engel at the Royal College of Surgeons in Ireland (Dublin, Ireland). The aim of this PhD project is to study the impact of ATP-gated purinergic signalling on seizures and the development of epilepsy. During the course of the project, the applicant will employ a multidisciplinary approach making use of a variety of in vitro and in vivo techniques including different mouse models and newly developed diagnostic devices. Applicants should have (or be expected to be awarded) a first class/upper second class honours degree (or equivalent) in neuroscience, biochemistry or an equivalent discipline.

Recent publications by the group: 

Alves et al., Epilepsia 58(9):1603-1614 (2017); Jimenez-Pacheco et al., J Neurosci 36(22):5920-32 (2016); Jimenez-Mateos et al., Sci Rep 3;5:17486 (2015); Jimenez-Mateos et al. Nat Med 18(7):1087-94 (2012); Engel et al. Brain 136:577-92 (2013)


  • Department: Physiology and Medical Physics
  • Main supervisor profile
  • Theme: Neuroscience, Epilepsy
  • Funding agency: Science Foundation Ireland


Studentship details: 

  • Stipend of €18,000/year (up to a maximum of 4 years )
  • Student fees of €6,900/year.
  • Project consumables budget of approximately €1000/month.
  • Dedicated thesis write up space in our new state-of-the-art library
  • Structured professional development and transferable skills training programme


The successful candidate should be able to demonstrate the following: 


  • An Honours Bachelor degree (grade 2.1 or above) in Neuroscience
  • Good communication skills
  • Strong organisational and administrative skills
  • Ability to work on one’s own initiative as well as in a multidisciplinary, team environment
  • Willingness to undertake training and career development
  • English language requirements for candidates who do not speak English as their first language: an IELTS score of 6.5 or above


  • Strong background in Neuroscience
  • Willingness to work with In Vivo Disease Models

Application process

Please apply here with the following:

  • Up-to-date curriculum vitae 
  • Scanned transcripts (preferred), or detailed degree grade breakdown
  • Completed application form (available here)
  • Contact details of two referees
  • Application deadline **extended to: Monday, 12 March 2018 at 10am.
  • Start date: 1 April 2018

Informal enquiries can be directed to

Mentors Dr Tobias Engel