Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Paediatric research

Below is an outline of the Paediatrics Professors' Publications for the period 2015 to 2016.


Prof. Alf Nicholson’s publications

Book Chapters in “European Mastercourse in Paediatrics”

Professor Nicholson author of chapters on: 

History Taking and Physical examination

Communication skills

Injuries Poisoning and apparent life –threatening events 

Sauer, Pieter JJ, Alf Nicholson, and David Neubauer. "Age determination in asylum seekers: physicians should not be implicated." European journal of pediatrics 3.175 (2016): 299-303.

Hamilton, Karina, William Macken, C. McGarvey, T. G. Matthews, and A. J. Nicholson. "Pedestrian deaths in children--potential for prevention." Irish medical journal 108, no. 1 (2015): 8-11.

Geoghegan, S., A. J. Nicholson, and E. J. Molloy. "Incorporating teaching in global child health into Irish medical school curriculum." Irish medical journal(2015).

A J. Nicholson (2016) Shaken baby syndrome, IMJ publications

A J. Nicholson (2016) Medical personnel and their role in sports concussion, IMJ publications

For a full list of Prof Nicholson's publications please refer to PubMed at 


Prof. Paul McNally's publications

Higgins, G., Fustero Torre, C., Tyrrell, J. McNally, P. et al. (2016). "Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa." Am J Physiol Lung Cell Mol Physiol 310(11): L1053-1061. 

McGovern E, McNally P, O'Sullivan M, Phelan E, Sumner K, Best DH, McMahon CJ. (2016)   “Infantile pulmonary capillary haemangiomatosis: a lethal form of pulmonary hypertension” Volume: 26, pp 663, Cardiology in the Young, DOI: 10.1017/S1047951115001006

Bojana Mirkovic, Michelle A Murray, Gillian M Lavelle, Kevin Molloy, Ahmed Abdul Azim, Cedric Gunaratnam, Fiona Healy, Dubhfeasa Slattery, Paul McNally et al (2015) “The role of short-chain fatty acids, produced by anaerobic bacteria, in the cystic fibrosis airway”, American journal of respiratory and critical care medicine, American Thoracic Society 192 (11): 1314-1324

Irene K Oglesby, Sebastian F Vencken, Raman Agrawal, Kevin Gaughan, Kevin Molloy, Gerard Higgins, Paul McNally, Noel G McElvaney, Marcus A Mall, Catherine M Greene (2015) “miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production”, European Respiratory Journal, Vol 46 (5), 1350-1360,  European Respiratory Society

For more of Prof McNally's publications please refer to Researchgate at

Prof. Martin White's publications

Casey, Jillian P., Patricia Goggin, Jennifer McDaid, Martin White, Sean Ennis, David R. Betts, Jane S. Lucas, Basil Elnazir, and Sally A. Lynch. "A case report of primary ciliary dyskinesia, laterality defects and developmental delay caused by the co-existence of a single gene and chromosome disorder." BMC medical genetics 16, no. 1 (2015): 45.

Perrem, L. M., O'Neill, R., O'Grady, M., & White, M. (2015). An audit of urinary tract infections in very low birth weight infants--what are we missing?.Irish medical journal.

For a full list of Prof White's publications check out PubMed at 

Prof. Alan Mortell's publications

Brendan O’Connor and Alan Mortell. 2016. Gastric Volvulus. In: Puri P, editor. Newborn Surgery, 4th Edition. Hodder Arnold, London. (In press)

Farhan Tareen and Alan Mortell. 2016. Cholecystectomy. In: Puri P, Höllwarth M, editors. Pediatric Surgery, Springer Surgery Atlas Series, 2nd Edition. Springer: Berlin, Heidelberg. (In press)

Abdominal radiography is not necessary in children with intussusception, Tareen F, McLaughlin D, Cianci F, Hoare SM, Sweeney B, Mortell A, Puri P, Pediatr Surg Int. 2015 Nov 6. [Epub ahead of print]

For a full list of Prof Mortell's publications please refer to PubMed at  


Prof. Naomi McCallion's publications

Neonatal discharge planning: could unscheduled reviews be reduced in the first 6 weeks of life? E Forman, N O Cathain, A Sills, S Cronin, A Foran, N McCallion. IMJ 2015; 108(7): 219-220.

Stapleton, P. J., Murphy, M., McCallion, N., Brennan, M., Cunney, R., & Drew, R. J. (2016). Outbreaks of extended spectrum beta-lactamase-producing Enterobacteriaceae in neonatal intensive care units: a systematic review.Archives of Disease in Childhood-Fetal and Neonatal Edition, 101(1), 72-78.

Forman, E., Cathin, N., Sills, A., Cronin, S., Foran, A., & McCallion, N. (2015). Neonatal discharge planning: could unscheduled reviews be reduced in the first six weeks of life?. Irish medical journal.

For more of Prof McCallion's publications check out Researchgate at 

Prof. Afif EL-Khuffash Publications

Commissioned Book Chapters 2015 – 2016 

EL-Khuffash A, McNamara PJ, Noori S: Neonatology: Questions and Controversies, 3rd Edition 2016 (Pathophysiology, diagnosis and outcome of hemodynamically significant ductus arteriosus in the very preterm neonate). Martin Kluckow and Itsvan Seri. 

EL-Khuffash A, Jain A, Breatnach CR: Neonatology: Questions and Controversies, 3rd Edition 2016 (Haemodynamics and Cardiology Section: Tissue Doppler Imaging in Neonates). Martin Kluckow and Itsvan Seri. 

EL-Khuffash A, McNamara PJ: Fetal and Neonatal Physiology, 5th Edition, 2015. (Oxygen Transport and Delivery Chapter). Richard Polin, Steve Abman, William Benitz & David Rowitch. Elsevier Publishing.  

Peer Reviewed Publications 2015 – 2016 

Levy PT, EL-Khuffash A. Pulmonary Arterial Hypertension after ibuprofen treatment in the first week of life? J Pediatr. 2016 Dec 8. pii: S0022-3476(16)31350-6. doi: 10.1016/j.jpeds.2016.11.047.

Breatnach CR, Franklin O, James AT, McCallion N, EL-Khuffash A. The Impact of a Hyperdynamic Left Ventricle on Right Ventricular Function Measurements in Preterm Infants with a Patent Ductus Arteriosus. Arch Dis Child Fetal Neonatal Ed. 2016, In press. 

Weisz D, McNamara PJ, EL-Khuffash A. Cardiac Biomarkers and Haemodynamically Significant Patent Ductus Arteriosus in Preterm Infants. Early Human Development. Early Hum Dev. 2016 Dec 17. pii: S0378-3782(16)30571-0. doi: 10.1016/j.earlhumdev.2016.12.007

Jain A, EL-Khuffash A, Kuipers BCW, Mohamed A, Connelly KA, Jankov JP, McNamara PJ, Mertens L. Quantitative Measurements of Left Ventricular Dimensions and Function in Healthy Term Neonates during the Transitional Period Using Conventional, Tissue Doppler and Speckle Tracking Echocardiography.  J Pediatr. 2016 Nov 28. pii: S0022-3476(16)31231-8. doi: 10.1016/j.jpeds.2016.11.003. 

Neary E, Ni Ainle F, EL-Khuffash A, Cotter M, Kirkham C, McCallion N. Plasma transfusion to prevent intraventricular haemorrhage in very preterm infants. Cochrane Database of Systematic Reviews 2016, Issue 9. Art. No.: CD012341. DOI: 10.1002/14651858.CD012341. 

Breatnach CR, Franklin O, McCallion N, EL-Khuffash A. The Effect of a Significant Patent Ductus Arteriosus on Doppler Flow Patterns of Pre-ductal Vessels: An assessment of the Brachiocephalic Artery. J Pediatr. 2017 Jan;180:279-281.

de Boode WP, Singh Y, Gupta S, Austin T, Bohlin K, Dempsey E, Groves AM, Horsberg Eriksen B, van Laere D, Molnar Z, Nestaas E, Rogerson SR, Schubert U, Tissot C, van der Lee R, van Overmeire B, EL-Khuffash A. Recommendations for Neonatologist Performed Echocardiography (NPE) in Europe: Consensus Statement endorsed by European Society for Paediatric Research (ESPR) and European Society for Neonatology (ESN). Pediatr Res. Pediatr Res. 2016 Oct;80(4):465-71.

Ting JY, Resende M, More K, Nicholls D, Weisz DE, EL-Khuffash A, Jain A, McNamara PJ. Predictors of Respiratory Instability in Neonates undergoing Patient Ductus Arteriosus Ligation after the Introduction of Targeted Milrinone Treatment. J Thorac Cardiovasc Surg. 2016 Aug;152(2):498-504.

Breatnach CR, Levy PT, James AT, Franklin O, EL-Khuffash A. Novel echocardiography methods in the functional assessment of the newborn heart. Neonatology. Neonatology. 2016 Jun 10;110(4):248-260. 

Weisz D, Martins F, Nield L, EL-Khuffash A, Jain A, McNamara PJ. Acetaminophen to avoid surgical ligation in extremely low gestational age neonates with persistent hemodynamically significant patent ductus arteriosus. J Perinatol. 2016 Aug;36(8):649-53.

EL-Khuffash A, Weisz D, McNamara PJ. Reflections of the changes in PDA management during the last 10 years. Arch Dis Child Fetal Neonatal Ed. 2016 Sep;101(5):F474-8.

James AT, Corcoran JD, Franklin O, EL-Khuffash A. Clinical Utility of Right Ventricular Fractional Area Change in Preterm Infants. Early Hum Dev. 2016 Jan;92:19-23.

EL-Khuffash A, James AT, Corcoran JD, Dicker P, Franklin O, Elsayed YN, Ting J, Sehgal A, Malikawi A, Harabor A, Soraisham AS, McNamara PJ.  A Patent Ductus Arteriosus Severity Score Predicts Chronic Lung Disease or Death before Discharge. J Pediatr. 2015 Dec;167(6):1354-1361.e2. 

James AT, Corcoran JD, Hayes B, Franklin O, EL-Khuffash A. The Effect of Antenatal Magnesium Sulfate Administration on left Ventricular Afterload and Myocardial Performance Measured using Deformation and Rotational Mechanics Imaging. J Perinatol. 2015 Nov;35(11):913-8. 

Breatnach C, Flanagan F, Corcoran JD, Franklin O, EL-Khuffash A. The use of Inhaled Nitric Oxide in a Tertiary Neonatal Intensive Care Unit in the Republic of Ireland. Ir Med J. 2015 Oct;108(9):275-8.

James AT, Corcoran JD, Mertens L, Franklin O, EL-Khuffash A. Ventricular Rotational Mechanics in Preterm Infants Less than 29 Weeks Gestation over the First Week after Birth. J Am Soc Echocardiogr. 2015 Jul;28(7):808-817.

EL-Khuffash A, James AT, Cleary A, Semberova J, Franklin O, Miletin J. Late Medical Therapy of Patent Ductus Arteriosus using Intravenous Paracetamol. Arch Dis Child Fetal Neonatal Ed. 2015 Apr;35(4):268-73.  

James AT, Corcoran JD, McNamara PJ, Franklin O, EL-Khuffash A. The Effect of Milrinone on Right and Left Ventricular Function when used as a Rescue Therapy for Term Infants with Pulmonary Hypertension. Cardiol Young. 2015 Jan 20:1-10. 

James AT, Bee C, Corcoran JD, McNamara PJ, Franklin O, EL-Khuffash A. Treatment of Premature Infants with Pulmonary Hypertension and Right Ventricular Dysfunction with Milrinone: A Case Series. J Perinatol. 2015 Apr;35(4):268-73.  

For more information please refer to

Dr Michael Riordan's publications

Cullinan, Noelle, Kathleen Mary Gorman, Michael Riordan, Mary Waldron, Timothy HJ Goodship, and Atif Awan. "Case Report: Benefits and Challenges of Long-term Eculizumab in Atypical Hemolytic Uremic Syndrome." Pediatrics(2015)

Refer to PubMed at to see more of Dr Riordan's publications

Prof Aengus O'Marcaigh's publications

O'Rafferty C, O'Brien M, Smyth E, Keane S, Robinson H, Lynam P, O'Marcaigh A, Smith OP, (2016).  Administration of G-CSF from day +6 post-allogeneic hematopoietic stem cell transplantation in children and adolescents accelerates neutrophil engraftment but does not appear to have an impact on cost savings., Journal Article,

O'Rafferty C, Kelly J, Storey L, Ryan C, O'Marcaigh A, Smith O, (2015).  Child and adolescent Down syndrome-associated leukaemia: the Irish experience., Irish Journal of Medical Science, 184 (4):877-882.

Connor S, O'Brien M, Irvine A, O'Marcaigh A, Smith O (2015). C3-C4 shingles post haematopoietic stem-cell transplantation. Archives of Disease in Childhood, 100 (2)

For more of Dr O'Marcaigh's publications please refer to Researchgate at 

Dr Seamus Hussey's publications

Manuscripts published in peer reviewed journals

Lafferty L, Tuohy M, Carey A, Sugrue S, Hurley M, Hussey S. Outcomes of exclusive enteral nutrition in paediatric Crohn's disease. Eur J Clin Nutr. 2016 Nov 23. doi: 10.1038/ejcn.2016.210. [Epub ahead of print]

Marcovitch L1, Nissan A, Mack D, Otley A, Hussey S, Mclean B, Lewis M, Croft N, Barakat FM, Griffiths AM, Turner D. Item Generation and Reduction Towards Developing a Patient Reported Outcome for Pediatric Ulcerative Colitis (TUMMY-UC). J Pediatr Gastroenterol Nutr. 2016 May 6. [Epub ahead of print]

Russell SE, Horan RM, Stefanska AM, Carey A, Leon G, Aguilera Pajubet M,  Statovci D 3 , Moran T, Fallon PG, Shanahan F, Brint EK, Melgar S, Hussey S, Walsh PT. IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation. Mucosal Immunol. 2016 Sep;9(5):1193-204

Bourke B, Hussey S. Chronic infections of the small intestine. Curr Opin Gastroenterol. 2015 Mar;31(2):104-10

Book Chapters

Chronic infections of the Small Intestine. Bourke B and Hussey S, in Yamada’s Textbook of Gastroenterology, 6th Edition (Editors: Podolsky and Shanahan)- October  2015

Gut microbial interactions. Wine E, Hussey S and Jones NL, in Walker’s Pediatric Gastrointestinal Disease: Physiology, Diagnosis, Management; 6th Edition (Editors:Kleinman, Goulet, Mieli-Vergagni, Sherman, Schneider) – December 2015

Helicobacter pylori in childhood. Crowley E and Hussey S , in Pediatric Gastrointestinal and Liver Disease; 5th Edition (Editors: Wyllie, Hyams, and Kay) – September 2015

For more of Dr Seamus Hussey's publications please refer to Researchgate at

Dr Carol Blackburn's publications

A Multicentre Retrospective Study of Management of Spontaneous Pneumothorax in Emergency Departments. Robinson PD, Blackburn C, et al. on behalf of the PREDICT network. Arch Dis Child 2015;100:10 918-923 Published Online First: 10 February 2015 doi:10.1136/archdischild-2014-30669.

Simulation based resuscitation training for staff in a Paediatric Emergency Department. A survey of trainees' attitudes and opinions. SO Donnell, M O Gorman, L Farren, C Blackburn. European Resuscitation Congress Oct 2015.